Europa
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América do Norte, América Central, Caraíbas
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| 1ª Mão | 2ª Mão | |||||||
|---|---|---|---|---|---|---|---|---|
| Santiago de Cuba |  | (2-2) |  | FC Ciego de Ávila | 1-1 | 1-1(7-6 g.p.) | ||
| Villa Clara |  | (4-3) |  | Artemisa | 1-1 | 3-2 |
| Fase | Data | Hora | |||||
|---|---|---|---|---|---|---|---|
| 0 | A | FC Pinar del Río | ADI | FC La Habana | 2025-04-19 | 21:00 | |
| 0 | A | FC Ciego de Ávila | ADI | FC Sancti Spíritus | 2025-05-03 | 20:00 | |
| 0 | A | FC Isla de La Juventud | ADI | Artemisa | 2025-05-09 | 21:00 | |
| 0 | A | FC La Habana | ADI | Artemisa | 2025-05-28 | 21:00 | |
| 0 | A | FC Pinar del Río | ADI | FC Isla de La Juventud | 2025-06-04 | 20:00 | |
| 0 | A | Villa Clara | ADI | Mayabeque | 2025-06-07 | 21:00 | |
| 0 | A | FC Sancti Spíritus | ADI | FC Camaguey | 2025-05-10 | 21:00 | |
| 0 | A | FC Isla de La Juventud | ADI | FC Pinar del Río | 2025-05-23 | 21:00 |
